I despise the new zoning system and its dependence on roads, you won't be building a car free city anytime soon. The lack of subways is very dissapointing too. I liked being able to choose my zoning type in SC4 because it gave you much more control. I really would have liked to see an option for mixed zoning with residential and commercial(a modern real life trend) to create walkable towns. They should rename the game Suburban Sprawl 5 because that is mostly what you're going to create.
The maps are much too small but that should be an easy addition for them.
There is a lot of potential here but in many ways it is a step back. EA has continued their trend of dumbing down games in order to reach the lowest common denominator.