Well, I think it would depend on how creative you are. What you think is nice and how you want to make it. There're plenty of tutorials available, you may adopt some of the ideas.
Your residential, commercial and Industry may not start up with nicely arranged buildings, but it will eventually boost up as you play longer. Many other tips is available too. I've learned a great lot from tips from here. Some of the Lots can be use to beautify your city, town or metropolis! I guessed by the time you reached the stage of metropolis, you'll be running of land to place the available lots from the download.
I did by trying everything and then bulldoze if I don't like it. Use the cheat for the simoleon. it may cost you for building and bulldozing.
